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High-Throughput Screening av mikrobielle isolater med innvirkning på Caenorhabditis elegans Helse

Article DOI: 10.3791/63860-v • 11:40 min • April 28th, 2022
April 28th, 2022 •
*1, *1, 1, 1
1Division of Biomedical and Life Sciences, Lancaster University
* These authors contributed equally

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Tarmmikrober kan positivt eller negativt påvirke helsen til verten via spesifikke eller konserverte mekanismer. Caenorhabditis elegans er en praktisk plattform for å skjerme for slike mikrober. Denne protokollen beskriver høy gjennomstrømningsscreening av 48 bakterielle isolater for påvirkning på nematodestressresistens, brukt som proxy for ormhelse.

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