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Immunology and Infection

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Generering av en mus spontan autoimmun tyreoiditt modell
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Generering av en mus spontan autoimmun tyreoiditt modell

Article DOI: 10.3791/64609-v • 04:39 min • March 17th, 2023
March 17th, 2023 •
1,2, 1,2, 1,2, 3, 1
1Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University, 2The Laboratory of Thyroid and Parathyroid Disease, West China Hospital of Sichuan University, 3State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center

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Flere typer dyremodeller av Hashimotos tyreoiditt har blitt etablert, som har spontan autoimmun tyroiditt i NOD-musen. H-2h4 mus er en enkel og pålitelig modell for HT-induksjon. Denne artikkelen beskriver denne tilnærmingen og evaluerer den patologiske prosessen for en bedre forståelse av SAT-murinmodellen.

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