Subcutaneous Electrodes

Subcutaneous electrodes are conductive sensors or stimulators placed beneath the skin to record biological electrical activity or deliver controlled currents, providing a stable interface between electronic devices and the body. In neuroscience, they detect voltage changes generated by nearby nerves or muscles, or activate excitable tissue through externally controlled electrical pulses; positioning below the skin can improve signal access compared with surface electrodes. Researchers use subcutaneous electrodes to monitor neural and peripheral physiological signals, study nerve function, and evaluate bioelectronic therapies. Their small size and minimally invasive placement also support long-term recordings and emerging neural interfaces.

Subcutaneous Electrodes - Related Videos

Research

JoVE EoE - Neurotherapeutics

Subcutaneous Trigeminal Nerve Stimulation to Relieve Neuropathic Facial Pain

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2025

Source: Jakobs, M., et al. Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain. J. Vis. Exp. (2017)This procedure demonstrates the implantation of subcutaneous electrodes for trigeminal nerve stimulation to treat neuropathic facial pain. The electrodes are tunneled subcutaneously from the affected facial region to an infraclavicular pocket, where they are connected to an internal pulse generator (IPG). The IPG delivers electrical stimulation, activating mechanoreceptor...

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

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Cited by 8 •

2017

Treating chronic or neuropathic facial pain can be challenging when medical or standard treatment fails. Subcutaneous nerve field stimulation is the least invasive form of neuromodulation and is used for chronic back pain. We applied this technology to treat chronic and neuropathic trigeminal facial pain.

Education

JoVE Core - Chemistry

Standard Electrode Potentials

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2020

On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...

Implantation of an Electrode Assembly in a Mouse Brain for Electrophysiological Recording

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2025

This video demonstrates a technique for implanting an electrode assembly into a mouse brain. The assembly contains bipolar electrodes to record activity from the hippocampus and a reference electrode to obtain baseline activity from the cerebellum. An anesthetized mouse is placed on a stereotaxic frame, and the electrode assembly is implanted in the target brain region. The animal is then allowed to recover before performing electrophysiological recording.

Fabrication of Amperometric Electrodes

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Cited by 8 •

2009

This protocol describes how to generate carbon fiber electrodes. The electrodes are subsequently used to detect catecholamine release from vesicles with carbon fiber amperometry.

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