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Journal / Immunology and Infection / Eine einfache und effiziente Methode zu…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Eine einfache und effiziente Methode zu konstruieren Mutant Vacciniavirusvektoren
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Eine einfache und effiziente Methode zu konstruieren Mutant Vacciniavirusvektoren

Article DOI: 10.3791/54171-v • 09:16 min • October 30th, 2016
October 30th, 2016 •
*1, *2,3, 1, 1,2,3, 1,2,3
1Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, 2Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University, 3School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University
* These authors contributed equally

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Vaccinia-Virus (VV) ist in der biomedizinischen Forschung und der Verbesserung der Gesundheit des Menschen weit verbreitet. Dieser Artikel beschreibt eine einfache, hocheffiziente Methode, um die VV-Genom mit Hilfe eines CRISPR-Cas9 System zu bearbeiten.

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Die Infektion Ausgabe 116 Vaccinia-Virus Genom Bearbeitung homologe Rekombination CRISPR Cas9
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