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Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture

Article DOI: 10.3791/54896-v • 09:06 min • December 22nd, 2016
December 22nd, 2016 •
*1, *2, 3, 3,4,5
1Department of Sports, Health & Leisure, College of Tourism, Leisure and Sports, Aletheia University, Tainan Campus, 2Department of Neurology, Mackay Memorial Hospital and Mackay Medical College, 3Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, 4Graduate Institute of Brain & Mind Sciences, College of Medicine, National Taiwan University, 5Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University
* These authors contributed equally

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This paper demonstrates the performance of acupuncture, epilepsy models, and the analysis of sleep in rodents. The acupuncture procedure and the identification of acupoints are described. Pilocarpine or pentylenetetrazol (PTZ) is used to induce epilepsy. Electrocorticogram (ECoG), electromyogram (EMG), brain temperature, and locomotor activity recordings are employed for sleep analysis.

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Epileptiform Electrocorticograms ECoGs Sleep Manipulation Rats Mice Acupuncture Animal Model Neuroscience Field Stereotaxic Surgery Lateral Cortical Electrodes Lateral Myogram Electrodes Sedation Toe Pinch Eye Ointment Spregg Dolly Rat Clippers Skull Hair Removal Disinfection Povidone Iodine Solution Ethanol Antibiotic Injection Stereotaxis Machine Ear Bar Caudal Incision Skull Tissue Removal Rotary Tool Drilling
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