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Journal / Immunology and Infection / En fluorescensbaserade lymfocyter analys Lämplig…
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Immunology and Infection

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En fluorescensbaserade lymfocyter analys Lämplig för high-throughput screening av små molekyler
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En fluorescensbaserade lymfocyter analys Lämplig för high-throughput screening av små molekyler

Article DOI: 10.3791/55199-v • 08:43 min • March 10th, 2017
March 10th, 2017 •
1, 2, 2, 2, 1,2,3
1Department of Microbiology, Infectiology and Immunology, Université de Montréal, 2Department of Pharmacology and Physiology, Université de Montréal, 3Molecular Biology Program, Université de Montréal

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Vi presenterar i den aktuella studien en ny fluorescensbaserad analys med användning av lymfocyter härledda från en transgen mus. Denna analys är lämplig för high-throughput screening (HTS) av små molekyler utrustade med egenskap av antingen inhibering eller främjande av lymfocytaktivering.

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Immunologi High-throughput screening fenotypisk screening mål baserad screening läkemedelsframtagning lymfocyter T-celler B-celler fluorescens grönt fluorescerande protein Nur77 immunosuppression aktivering
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