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En Drosophila In Vivo skade Model til at studere Neuroregeneration i perifere og centrale nervesystem

Article DOI: 10.3791/57557-v • 09:55 min • May 5th, 2018
May 5th, 2018 •
*1, *1, 1, 1,2
1Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, 2Department of Pathology and Laboratory Medicine, University of Pennsylvania
* These authors contributed equally

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Vi præsenterer her, en protokol bruger Drosophila sensoriske neuron - dendritiske arborization (da) neuron skade model, som kombinerer i vivo live imaging, to-foton laser axotomy/dendriotomy og kraftfuld flyve genetiske værktøjskassen, som en platform for screening potentielle initiativtagere og hæmmere af neuroregeneration.

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Medicin spørgsmål 135 Drosophila sensoriske neuron dendritiske arborization neuron neurale skade neuroregeneration axotomy dendriotomy PNS CNS
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