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En Middle cerebral arterie okklusion teknik til inducerende post-slagtilfælde depression i rotter

Article DOI: 10.3791/58875-v • 04:38 min • May 22nd, 2019
May 22nd, 2019 •
*1, *2, 3, 1, 1, 1, 1, 1, 1, 1
1Department of Anesthesiology and Critical Care, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 3Department of Biophysics and Biochemistry, Faculty of Biology, Ecology, and Medicine, Oles Honchar Dnipro National University
* These authors contributed equally

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Her præsenterer vi en protokol til at fremkalde post-slagtilfælde depression i rotter ved at okkoere den midterste cerebral arterien via den indre carotis arterien. Vi bruger Porsolt tvungen svømme test og saccharosepræference testen for at bekræfte og evaluere inducerede depressive stemninger.

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Opførsel iskæmisk slagtilfælde post slag depression rotte model midterste cerebral arterie okklusion infarkt volumen hjerneødem Porsolt tvungen svømme test saccharosepræference test
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