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Una técnica de oclusión de la arteria cerebral media para inducir la depresión post-accidente cerebrovascular en ratas

Article DOI: 10.3791/58875-v • 04:38 min • May 22nd, 2019
May 22nd, 2019 •
*1, *2, 3, 1, 1, 1, 1, 1, 1, 1
1Department of Anesthesiology and Critical Care, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 3Department of Biophysics and Biochemistry, Faculty of Biology, Ecology, and Medicine, Oles Honchar Dnipro National University
* These authors contributed equally

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Aquí presentamos un protocolo para inducir la depresión post-accidente cerebrovascular en ratas, ocluendo la arteria cerebral media a través de la arteria carótida interna. Usamos la prueba de natación forzada de Porsolt y la prueba de preferencia de sacarosa para confirmar y evaluar Estados de ánimo depresivos inducidos.

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Comportamiento problema 147 accidente cerebrovascular isquémico depresión poststroke modelo de rata oclusión de la arteria cerebral media volumen de infarto edema cerebral prueba de natación forzada de Porsolt prueba de preferencia de sacarosa
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