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Een middelste cerebrale slagader occlusie techniek voor het induceren van post-takt depressie bij ratten

Article DOI: 10.3791/58875-v • 04:38 min • May 22nd, 2019
May 22nd, 2019 •
*1, *2, 3, 1, 1, 1, 1, 1, 1, 1
1Department of Anesthesiology and Critical Care, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, 3Department of Biophysics and Biochemistry, Faculty of Biology, Ecology, and Medicine, Oles Honchar Dnipro National University
* These authors contributed equally

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Hier presenteren we een protocol te induceren post-takt depressie bij ratten door afsluiter het midden cerebrale slagader via de interne halsslagader. We gebruiken de Porsolt geforceerde zwem test en de sacharose voorkeur test om geïnduceerde depressieve stemmingen te bevestigen en te evalueren.

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Gedrag ischemische beroerte poststroke depressie rat model Midden cerebrale slagader occlusie infarct volume hersenoedeem Porsolt gedwongen zwemmen test sacharose voorkeur test
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