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JoVE Journal Neuroscience
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Afstamming Tracering van induceerbare fluorescerend gelabelde stamcellen in het volwassen muizenbrein

Article DOI: 10.3791/63998-v • 09:44 min • May 20th, 2022
May 20th, 2022 •
1,2, 2, 3, 1,2
1Graduate School of Biomedical Science and Engineering, University of Maine, 2Department of Neurosurgery, Ohio State University Wexner Medical Center, 3Boston Children’s Hospital, Harvard Medical School

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Het vermogen om stamcellen en hun nakomelingen permanent te markeren met een fluorofoor met behulp van een induceerbare transgene lineage tracing muislijn maakt ruimtelijke en temporele analyse van activering, proliferatie, migratie en / of differentiatie in vivo mogelijk. Lineage tracing kan nieuwe informatie onthullen over lineage commitment, reactie op interventie(s) en multipotentie.

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Neurowetenschappen Nummer 183
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