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Journal / Cancer Research / Zebrafisklarver som model til evaluering af…
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Cancer Research
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JoVE Journal Cancer Research
Zebrafisklarver som model til evaluering af potentielle radiosensibilisatorer eller beskyttere
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Zebrafisklarver som model til evaluering af potentielle radiosensibilisatorer eller beskyttere

Article DOI: 10.3791/64233-v • 04:53 min • August 25th, 2022
August 25th, 2022 •
*1,3, *1,3, 1,4, 2,3, 2, 1
1Tumor microenvironment and animal models lab, Institute of Life Sciences, 2Vascular Biology lab, Institute of Life Sciences, 3Regional Centre for Biotechnology, 4School of Biotechnology, KIIT University
* These authors contributed equally

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Zebrafisken er for nylig blevet udnyttet som model til at validere potentielle strålingsmodifikatorer. Denne protokol beskriver de detaljerede trin til at bruge zebrafiskembryoner til strålingsbaserede screeningsforsøg og nogle observationsmetoder til evaluering af effekten af forskellige behandlinger og stråling.

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Zebrafisklarver model radiosensibilisatorer beskyttere strålingsforskning in vivo-model strålingsinduceret DNA-skade kræftundersøgelser strålingsmodifikatorer strålebehandling lægemiddelscreening toksicitetsvurdering røntgenstrålingseksponering procedure pålidelighed reproducerbarhed
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