Name: 治療抵抗性うつ病に対するロボット投与fMRI誘導個別化経頭蓋磁気刺激療法 (動画) | JoVE Journal
Uploaded: 2026-04-10T12:43:00.000+00:00
Duration: 13 min 18 s
Description: 学ぶ、fMRI誘導ロボット経頭蓋磁気刺激療法による治療抵抗性うつ病への個別化治療法。DLPFC標的決定と神経ナビゲーションを用いた正確な刺激配分により、臨床応答率52%と寛解率33%を達成する革新的プロトコルです。

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</ol>

<table><tbody><tr><td>64チャンネルのヘッド&ネックコイル</td><td>シーメンス</td><td>10606850</td><td></td></tr><tr><td>クラウド計算サービス</td><td>アマゾン</td><td>https://aws.amazon.com/?refid=536ef9fe-bc1d-4318-ae84-3df0523ed98a</td><td></td></tr><tr><td>コボット</td><td>アクシラム</td><td>https://www.axilumrobotics.com/en/</td><td>このコボットはニューロナビゲーションシステムとコイルと統合されたソフトウェアおよびハードウェアの特定統合を備えています。</td></tr><tr><td>DCM2NIIX</td><td>ローダーン研究所</td><td>https://www.nitrc.org/plugins/mwiki/index.php/dcm2nii:MainPage;https://github.com/rordenlab/dcm2niix</td><td>参照 https://www.nitrc.org/plugins/mwiki/index.php/dcm2nii:MainPage;https://github.com/rordenlab/dcm2niix 操作マニュアル用とnbsp;</td></tr><tr><td>fMRIPrep</td><td>ニュップ</td><td>https://fmriprep.org/en/stable/api.html</td><td>fMRI前処理用のオープンソースソフトウェアツールで、操作マニュアルは https://fmriprep.org/en/stable/ を参照してください。</td></tr><tr><td>MRI装置</td><td>シーメンス</td><td>166026</td><td>3 テスラ場の強さ。</td></tr><tr><td>MRICron</td><td>NITRC</td><td>https://www.nitrc.org/projects/mricron</td><td>MRI画像を可視化するためのオープンソースソフトウェアツールは、操作マニュアル https://www.nitrc.org/projects/mricron を参照してください。</td></tr><tr><td>ニューロナビゲーションカメラ</td><td>ノーザン・デジタル社</td><td>P7-11191</td><td>このニューロナビゲーションカメラと、同じメーカーの同系列の他のものも含まれています。TMSナビゲーターと互換性があります</td></tr><tr><td>TMSコイル</td><td>マグベンチャー</td><td>9016年 E0151</td><td>このコイルはコボットのロボットアームとハードウェア統合されるよう設計されており、独自の冷却システムを備えています。</td></tr><tr><td>TMSニューロナビゲーションシステム</td><td>ローカライト</td><td>10225</td><td>このニューロナビゲーションシステムは、コボットおよびTMS刺激器と統合された特定のソフトウェア機能を備えています。</td></tr><tr><td>TMS刺激器</td><td>マグベンチャーA/S</td><td>&nbsp;9016E0721</td><td>このTMS刺激システムは、コイルおよびニューロナビゲーションシステムと統合して刺激フィードバック(例:パルス数、運動誘発電位記録)を用いるよう設計されています。&nbsp;</td></tr></tbody></table>

治療抵抗性うつ病に対するロボット投与fmri誘導個別化経頭蓋磁気刺激療法

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression

治療抵抗性うつ病に対するロボット投与fMRI誘導個別化経頭蓋磁気刺激療法

Improving the outcomes of transcranial magnetic stimulation (TMS) therapy for treatment-resistant depression may be achieved by personalizing the ...

robotically-delivered-fmri-guided-personalized-transcranial-magnetic

Research

JoVE Journal

Neuroscience

神経科学

出典: Dunlop, K., et al.治療抵抗性大うつ病性障害の治療としての MRI ガイド下 dmPFC-rTMS。J. Vis. 経験。(2015年)このビデオでは、うつ病を治療するために背内側前頭前野 (dmPFC) を標的とする MRI ガイド下反復経頭蓋磁気刺激 (rTMS)...

背内側前頭前野へのMRIガイド下反復経頭蓋磁気刺激

ここでは、大うつ病性障害の実験的治療として、背内側前頭前皮質へのMRIガイド下反復経頭蓋磁気刺激の手順を概説します。...

治療抵抗性大うつ病性障害の治療薬としてdmPFC-のrTMSをMRIガイド

ここでは、深い経頭蓋磁気刺激（DTMS）システムを使用して、大うつ病性障害の治療のための方法論を概説したプロトコルを提示します。...

Brainsway H1-コイルを使用した反復ディープ経頭蓋磁気刺激を用いた臨床うつ病の治療

本プロトコールは、反復経頭蓋磁気刺激(rTMS)の適用を記載しており、ここで、眼底前頭前皮質(DLPFC)のサブ領域は、fMRIベースのニューロナビゲーションシステムの支援の下で、最も強い機能的反相関を有する背外側前頭前野(DLPFC)のサブ領域が刺激標的として位置付けられた。...

fMRIベースのターゲティング法を用いたうつ病の個別化rTMS治療

皮質ネットワークの脳波記録(TMS-EEG)マッピングと組み合わせたパーソナライズされた経頭蓋磁気刺激のための新しいプロトコルで、複数の磁気共鳴画像法(MRI)データモダリティによって通知されます。...

リアルタイム皮質ネットワークマッピングのためのニューロイメージングガイド下TMS-EEG

本プロトコルは、治療抵抗性大うつ病に対する反復経頭蓋磁気刺激の正確かつ患者中心の適用ガイドを提供します。正確なコイル定位、可調整刺激用量、厳格な安全対策、急性期および維持セッションにおける快適さ、再現性、長期的な臨床効果を最大化する戦略の詳細が示されています。...

うつ病に対する従来の反復経頭蓋磁気刺激:段階的なプロトコル

閃光は、大脳皮質の視覚的に敏感な領域に経頭蓋磁気刺激（TMS）を適用することによって誘導することができる光の一時的な知覚です。我々は、閃光のしきい値を決定するための標準プロトコルを示し、知覚閃光を定量化し、分析するための新規な方法を紹介。...

経頭蓋磁気刺激による閃光を文書化するための斬新なアプローチ

この記事では、デフォルトのネットワーク上の脳刺激の効果を調べるためにTMSとfMRIの組み合わせに関連する方法論と考慮事項を検討する。...

デフォルトモードのネットワークを検査する経頭蓋磁気刺激とfMRIを組み合わせ

この記事では、我々は、動機のphosphenicプレゼンテーションを誘導TMSで視覚的に関連する状態依存性の影響を調べる。...

TMSの状態 - 依存性の効果：動機の閃光の挙動を見

この記事では、我々はNeuronetics NeuroStar...

NeuroStar TMSデバイス：うつ病の治療薬としてFDA承認されたプロトコルを実施

学ぶ、fMRI誘導ロボット経頭蓋磁気刺激療法による治療抵抗性うつ病への個別化治療法。DLPFC標的決定と神経ナビゲーションを用いた正確な刺激配分により、臨床応答率52%と寛解率33%を達成する革新的プロトコルです。

治療抵抗性うつ病に対するロボット投与fMRI誘導個別化経頭蓋磁気刺激療法

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