Sieghart Sopper Department of Internal Medicine V (Hematology & Oncology) Medical University Innsbruck Biography Publications Institution JoVE Articles Sieghart Sopper has not added a biography. If you are Sieghart Sopper and would like to personalize this page please email our Author Liaison for assistance. Publications The Influence of Stromal Cells and Tumor-microenvironment-derived Cytokines and Chemokines on CD3(+)CD8(+) Tumor Infiltrating Lymphocyte Subpopulations Oncoimmunology. 2017 | Pubmed ID: 28680763 Single Cell Immune Profiling by Mass Cytometry of Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia Treated with Nilotinib Haematologica. Aug, 2017 | Pubmed ID: 28522574 Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2017 | Pubmed ID: 28056193 Pre-infection Transcript Levels of FAM26F in Peripheral Blood Mononuclear Cells Inform About Overall Plasma Viral Load in Acute and Post-acute Phase After Simian Immunodeficiency Virus Infection The Journal of General Virology. Dec, 2016 | Pubmed ID: 27902344 Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche Biochimica Et Biophysica Acta. Dec, 2016 | Pubmed ID: 27751894 Ionophore Antibiotics As Cancer Stem Cell-Selective Drugs: Open Questions The Oncologist. Aug, 2016 | Pubmed ID: 27486200 On-demand Erythrocyte Disposal and Iron Recycling Requires Transient Macrophages in the Liver Nature Medicine. Aug, 2016 | Pubmed ID: 27428900 Successful Management of Mixed Chimerism After Bone Marrow Transplant in Beta-thalassemia Major American Journal of Hematology. Sep, 2016 | Pubmed ID: 27239048 High Prevalence of Side Population in Human Cancer Cell Lines Oncoscience. 2016 | Pubmed ID: 27226981 Leukemic Stem Cell Quantification in Newly Diagnosed Patients With Chronic Myeloid Leukemia Predicts Response to Nilotinib Therapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2016 | Pubmed ID: 27006491 Opiate Receptor Blockade on Human Granulosa Cells Inhibits VEGF Release Reproductive Biomedicine Online. Mar, 2016 | Pubmed ID: 26803207 Optimized Stem Cell Detection Using the DyeCycle-Triggered Side Population Phenotype Stem Cells International. 2016 | Pubmed ID: 26798352 Increased BST2 Expression During Simian Immunodeficiency Virus Infection is Not a Determinant of Disease Progression in Rhesus Monkeys Retrovirology. Nov, 2015 | Pubmed ID: 26554913 Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques PloS One. 2015 | Pubmed ID: 26551355 Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics Stem Cells Translational Medicine. Sep, 2015 | Pubmed ID: 26136502 OMIP-026: Phenotypic Analysis of B and Plasma Cells in Rhesus Macaques Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2015 | Pubmed ID: 26115002 Treg(s) in Cancer: Friends or Foe? Journal of Cellular Physiology. Nov, 2015 | Pubmed ID: 25913194 Modulation of Immune Cell Functions by the E3 Ligase Cbl-b Frontiers in Oncology. 2015 | Pubmed ID: 25815272 Characterization of B and Plasma Cells in Blood, Bone Marrow, and Secondary Lymphoid Organs of Rhesus Macaques by Multicolor Flow Cytometry Journal of Leukocyte Biology. Jan, 2015 | Pubmed ID: 25341725 The Side Population of Ovarian Cancer Cells Defines a Heterogeneous Compartment Exhibiting Stem Cell Characteristics Oncotarget. Aug, 2014 | Pubmed ID: 25216521 Identification of Molecular Sub-networks Associated with Cell Survival in a Chronically SIVmac-infected Human CD4+ T Cell Line Virology Journal. Aug, 2014 | Pubmed ID: 25163480 Host Factors Determine Differential Disease Progression After Infection with Nef-deleted Simian Immunodeficiency Virus The Journal of General Virology. Oct, 2014 | Pubmed ID: 24928910 Increases in CSF Dopamine in HIV Patients Are Due to the Dopamine Transporter 10/10-repeat Allele Which is More Frequent in HIV-infected Individuals Journal of Neural Transmission (Vienna, Austria : 1996). Oct, 2013 | Pubmed ID: 24057505 Cytokine Levels in CSF and Neuropsychological Performance in HIV Patients Journal of Neurovirology. Jun, 2012 | Pubmed ID: 22528475 Stable Multi-infection of Splenocytes During SIV Infection--the Basis for Continuous Recombination Retrovirology. Apr, 2012 | Pubmed ID: 22524249 DyeCycle Violet Used for Side Population Detection is a Substrate of P-glycoprotein Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jun, 2012 | Pubmed ID: 22407964 Increased APOBEC3G and APOBEC3F Expression is Associated with Low Viral Load and Prolonged Survival in Simian Immunodeficiency Virus Infected Rhesus Monkeys Retrovirology. Sep, 2011 | Pubmed ID: 21955401 Potential Role of Regulatory T Cells in Reversing Obesity-linked Insulin Resistance and Diabetic Nephropathy Diabetes. Nov, 2011 | Pubmed ID: 21911743 Definition of Leukocyte Subsets in Primate Central Nervous System by Polychromatic Flow Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jun, 2011 | Pubmed ID: 21425237 Flow Cytometric Characterization of the Lymphocyte Composition in a Variety of Mucosal Tissues in Healthy Rhesus Macaques Journal of Medical Primatology. Feb, 2011 | Pubmed ID: 20698929 Measurement of Soluble Inflammatory Mediators in Cerebrospinal Fluid of Human Immunodeficiency Virus-positive Patients at Distinct Stages of Infection by Solid-phase Protein Array Journal of Neurovirology. Sep, 2009 | Pubmed ID: 20001608 Susceptibility to Simian Immunodeficiency Virus Ex Vivo Predicts Outcome of a Prime-boost Vaccine After SIVmac239 Challenge Journal of Acquired Immune Deficiency Syndromes (1999). Oct, 2009 | Pubmed ID: 19644382 Mucosal Prior to Systemic Application of Recombinant Adenovirus Boosting is More Immunogenic Than Systemic Application Twice but Confers Similar Protection Against SIV-challenge in DNA Vaccine-primed Macaques Virology. Jan, 2009 | Pubmed ID: 19027133 CD4 Deficits and Disease Course Acceleration Can Be Driven by a Collapse of the CD8 Response in Rhesus Macaques Infected with Simian Immunodeficiency Virus AIDS (London, England). Jul, 2008 | Pubmed ID: 18614867 Disruption of Excitatory Amino Acid Transporters in Brains of SIV-infected Rhesus Macaques is Associated with Microglia Activation Journal of Neurochemistry. Jan, 2008 | Pubmed ID: 17986224 Memantine Upregulates BDNF and Prevents Dopamine Deficits in SIV-infected Macaques: a Novel Pharmacological Action of Memantine Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Aug, 2008 | Pubmed ID: 17971830 Intrathecal Viral Replication and Cerebral Deficits in Different Stages of Human Immunodeficiency Virus Disease Journal of Neurovirology. Jun, 2007 | Pubmed ID: 17613712 Enrichment and Persistence of Virus-specific CTL in the Brain of Simian Immunodeficiency Virus-infected Monkeys is Associated with a Unique Cytokine Environment Journal of Immunology (Baltimore, Md. : 1950). May, 2007 | Pubmed ID: 17442965 Caspase Inhibition in Apoptotic T Cells Triggers Necrotic Cell Death Depending on the Cell Type and the Proapoptotic Stimulus Journal of Cellular Biochemistry. Apr, 2006 | Pubmed ID: 16365881 Early Impairment in Dopaminergic Neurotransmission in Brains of SIV-infected Rhesus Monkeys Due to Microglia Activation Journal of Neurochemistry. Oct, 2005 | Pubmed ID: 16190867 HIV-infection of the Central Nervous System: the Tightrope Walk of Innate Immunity Molecular Immunology. Feb, 2005 | Pubmed ID: 15488609 Caspase Inhibitors As a Supplement in Immune Activation Therapies to Achieve Eradication of HIV in Its Latent Reservoirs Annals of the New York Academy of Sciences. Dec, 2003 | Pubmed ID: 15033722 Replication, Immunogenicity, and Protective Properties of Live-attenuated Simian Immunodeficiency Viruses Expressing Interleukin-4 or Interferon-gamma Virology. Jan, 2003 | Pubmed ID: 12573592 Impact of Simian Immunodeficiency Virus (SIV) Infection on Lymphocyte Numbers and T-cell Turnover in Different Organs of Rhesus Monkeys Blood. Feb, 2003 | Pubmed ID: 12393472 Caspase Inhibitors Induce a Switch from Apoptotic to Proinflammatory Signaling in CD95-stimulated T Lymphocytes European Journal of Immunology. Sep, 2002 | Pubmed ID: 12207331 Caspase Inhibition Activates HIV in Latently Infected Cells. Role of Tumor Necrosis Factor Receptor 1 and CD95 The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11854296 The Role of the Envelope Glycoprotein in the Depletion of T Helper Cells in Human Immunodeficiency Virus Infection Pathology Oncology Research : POR. 1997 | Pubmed ID: 11173628 Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies Roman Crazzolara1, Gabriele Kropshofer1, Michael Steurer2, Sieghart Sopper2,3, Wolfgang Schwinger4 1Department of Pediatrics, Medical University Innsbruck, 2Department of Internal Medicine V (Hematology & Oncology), Medical University Innsbruck, 3Tyrolean Cancer Research Institute, 4Department of Pediatrics, Medical University Graz JoVE 56002 발생학 Harnessing the DNA Dye-triggered Side Population Phenotype to Detect and Purify Cancer Stem Cells from Biological Samples Maximilian Boesch*1,2,3, Elisabeth Hoflehner2,3, Dominik Wolf2,3,4, Guenther Gastl2, Sieghart Sopper*2,3 1Institute of Immunobiology, Kantonsspital St. Gallen, 2Internal Medicine V, Medical University of Innsbruck, 3Tyrolean Cancer Research Institute (TKFI), 4Medical Clinic III, Oncology, Hematology, Immunoncology and Rheumatology, University Clinic Bonn (UKB) JoVE 55634 암 연구학
Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies Roman Crazzolara1, Gabriele Kropshofer1, Michael Steurer2, Sieghart Sopper2,3, Wolfgang Schwinger4 1Department of Pediatrics, Medical University Innsbruck, 2Department of Internal Medicine V (Hematology & Oncology), Medical University Innsbruck, 3Tyrolean Cancer Research Institute, 4Department of Pediatrics, Medical University Graz JoVE 56002 발생학
Harnessing the DNA Dye-triggered Side Population Phenotype to Detect and Purify Cancer Stem Cells from Biological Samples Maximilian Boesch*1,2,3, Elisabeth Hoflehner2,3, Dominik Wolf2,3,4, Guenther Gastl2, Sieghart Sopper*2,3 1Institute of Immunobiology, Kantonsspital St. Gallen, 2Internal Medicine V, Medical University of Innsbruck, 3Tyrolean Cancer Research Institute (TKFI), 4Medical Clinic III, Oncology, Hematology, Immunoncology and Rheumatology, University Clinic Bonn (UKB) JoVE 55634 암 연구학
