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Mapping Bakterielle Functional Netzwerke und Pathways in

Article DOI: 10.3791/4056-v • 14:06 min • November 12th, 2012
November 12th, 2012 •
*1, *2,3, 1,2, 1,2
1Department of Molecular Genetics, University of Toronto, 2Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, 3Department of Biochemistry, Research and Innovation Centre, University of Regina
* These authors contributed equally

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Systematische, groß angelegte synthetische genetische (Gen-Gen-oder Epistase) Interaktion Bildschirme können verwendet werden, um genetische Redundanz und Weg cross-talk zu erkunden. Hier haben wir eine High-Throughput-quantitative synthetischen genetischen array Screening-Technologie beschreiben, bezeichnet ESGA dass wir für die Aufklärung epistatische Beziehungen und erforschen genetische Interaktion Netze in den entwickelten

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Genetik Molekularbiologie Medizin Biochemie Mikrobiologie Erschwerende Linderung Konjugation Doppelmutante, Genetische Interaktion Gram-negative Bakterien homologe Rekombination Netzwerk synthetischen Letalität oder Krankheit Suppression
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