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Combinato

Article DOI: 10.3791/51612-v • 18:40 min • October 16th, 2014
October 16th, 2014 •
1, 2, 2, 3, 3, 1, 2, 3,4
1Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Los Angeles (UCLA), 2PerkinElmer, 3Department of Dermatology, Johns Hopkins University School of Medicine, 4Department of Medicine, Division of Infectious Diseases, Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine

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Combinato imaging ottico e μCT in un modello murino di infezione impianto ortopedico, utilizzando un ceppo ingegnerizzato bioluminescente di Staphylococcus aureus, purché la capacità di monitorare in maniera non invasiva e longitudinalmente la dinamica della infezione batterica, così come la risposta infiammatoria corrispondente e cambiamenti anatomici nel osso.

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Infezione imaging ottico CT bioluminescenza fluorescenza stafilococco infezione infiammazione osso ortopedico protesi biofilm
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