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Developmental Biology

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JoVE Journal Developmental Biology
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Een eenvoudige methode om Kinases te identificeren die de embryonale stamcelpluripotency reguleren door middel van high-throughput inhibitor screening

Article DOI: 10.3791/55515-v • 07:18 min • May 12th, 2017
May 12th, 2017 •
1, 2,3, 1
1The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, 2Department of Cancer Biology, Dana-Farber Cancer Institute, 3Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

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Hier presenteren we een kwantitatief en schaalbaar protocol voor het uitvoeren van gerichte kleine molecuulschermen voor kinase-regulatoren van de naïeve-primed pluripotente transitie.

Tags

Ontwikkelingsbiologie Uitgave 123 Proteïne Kinase Embryonale Stamcellen Pluripotency Naïeve Primêre Transitie Kinase Inhibitors High-Throughput Screen
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