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Virus leverans av CRISPR guider till murina prostatan för gen ändring
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Virus leverans av CRISPR guider till murina prostatan för gen ändring

Article DOI: 10.3791/57525-v • 06:21 min • April 27th, 2018
April 27th, 2018 •
1, 1, 2, 2, 1
1Department of Clinical Medicine, Aarhus University, 2GDD, Cancer Cell Biology Program, National Cancer Research Center (CNIO)

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Det här protokollet beskriver en nyligen etablerade metod för virus leverans till murina prostatan. Använder antingen CRISPR/Cas9-teknik, gen överuttryck eller Cre recombinase leverans, tekniken tillåter ortotop ändring av genuttryck och implementerar en ny musmodell för prostatacancer.

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Cancerforskning fråga 134 prostatacancer editering genterapi gen ändring virus leverans virus injektion CRISPR/Cas9 adeno-associerade virus i vivo tumör modell tumör initiering
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