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Journal / Bioengineering / Nanosensorer att upptäcka proteas aktivitet In…
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Bioengineering

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JoVE Journal Bioengineering
Nanosensorer att upptäcka proteas aktivitet In Vivo för noninvasiv diagnostik
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Nanosensorer att upptäcka proteas aktivitet In Vivo för noninvasiv diagnostik

Article DOI: 10.3791/57937-v • 10:50 min • July 16th, 2018
July 16th, 2018 •
1, 1, 1,2,3,4,5
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech College of Engineering and Emory School of Medicine, 2Parker H. Petit Institute of Bioengineering and Bioscience, 3Institute for Electronics and Nanotechnology, Georgia Tech, 4Integrated Cancer Research Center, Georgia Tech, 5The Georgia Immunoengineering Consortium, Emory University and Georgia Tech

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Proteaser är hårt reglerade enzymer som är involverade i grundläggande biologiska processer och dysreglerad proteas aktivitet enheter progression av komplexa sjukdomar såsom cancer. Denna metods mål är att skapa nanosensorer som mäter proteas aktivitet i vivo genom att producera en klyvning-signal som är detekterbar från värd urin och diskriminerar sjukdom.

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Bioteknik fråga 137 syntetiska biomarkörer activity based sonder proteaser nanosensorer nanopartiklar urin diagnostik
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