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Fabrikasjon av Anisotrop polymere kunstig Antigen presentere celler for CD8 + T celle aktivering
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Fabrikasjon av Anisotrop polymere kunstig Antigen presentere celler for CD8 + T celle aktivering

Article DOI: 10.3791/58332-v • 10:16 min • October 12th, 2018
October 12th, 2018 •
*1, *1, 1, 2
1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine
* These authors contributed equally

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Her presenterer vi en protokoll for å raskt og reproduserbar generere biologisk inspirert, biologisk nedbrytbart articifical antigen presentere celler (aAPC) med tunable størrelse, form og overflate protein presentasjon for T celle ekspansjon ex vivo eller i vivo .

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Miljøfag problemet 140 aAPC immunoengineering polymer Anisotrop partikler figur
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