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Analyse der Krebs Zellinvasion und anti-metastatischen Drogen-Screening mit Hydrogel Micro-Kammer Array (HMCA)-basierte Platten
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Analyse der Krebs Zellinvasion und anti-metastatischen Drogen-Screening mit Hydrogel Micro-Kammer Array (HMCA)-basierte Platten

Article DOI: 10.3791/58359-v • 08:33 min • October 25th, 2018
October 25th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1
1Physics Department, Bar-Ilan University

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Eine HMCA-basierte Speicherfolie wird für Invasion Testleistung vorgestellt. Diese Platte erleichtert die Bildung von dreidimensionalen (3D) Tumor Sphäroide und die Messung der Krebs Zelle eindringen in die extrazelluläre Matrix (ECM). Die Invasion-Assay-Quantifizierung wird durch halbautomatische Analyse erreicht.

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Cancer Research Ausgabe 140 mehrzelligen 3D-Objekte Sphäroid Hydrogel Mikro-Kammer Invasion Assay ECM image-Analysen kollektive Invasion 3D Culture Modell
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