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Journal / Immunology and Infection / Billeddannelse den humane immunologiske synapse
JoVE Journal
Immunology and Infection

이 콘텐츠 오픈 액세스로 구독없이 시청하실 수 있습니다.

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Billeddannelse den humane immunologiske synapse
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Billeddannelse den humane immunologiske synapse

Article DOI: 10.3791/60312-v • 09:37 min • December 26th, 2019
December 26th, 2019 •
*1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 3, 1,2, *1,2
1Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-Universidad Autónoma de Madrid, 2Departamento de Bioquímica, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Facultad de Medicina, Universidad Autónoma de Madrid, 3Unidad de Audiovisuales, Facultad de Medicina, Universidad Autónoma de Madrid
* These authors contributed equally

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Denne protokol billeder både den immunologiske synapse dannelse og den efterfølgende polariserede sekretoriske trafik mod den immunologiske synapse. Cellulære konjugater blev dannet mellem en super antigen-pulserende Raji-celle (fungerer som en antigen-præsenterer celle) og en Jurkat klon (fungerer som en Effector hjælper T lymfocyt).

Tags

Immunologi og infektion T-lymfocytter antigen-præsenterer celler immunologisk synapse microtubule-organisere-Center polariseret trafik multivesikulære organer
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