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Journal / Cancer Research / 肺扁平上皮癌進行をモデル化する多次元共培養システム…
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Cancer Research

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JoVE Journal Cancer Research
肺扁平上皮癌進行をモデル化する多次元共培養システム
A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
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A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
Impedance-based Real-time Measurement of Cancer Cell Migration and Invasion
Journal (Cancer Research)
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肺扁平上皮癌進行をモデル化する多次元共培養システム

Article DOI: 10.3791/60644-v • 07:53 min • March 17th, 2020
March 17th, 2020 •
1, 1, 1, 1
1Oncology R&D group, Pfizer Worldwide Research and Development

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肺扁平上皮癌(LUSC)進行中の組織構造変化を、がん関連線維芽細胞(CAF)との3次元(3D)共培養で捉えるin vitroモデルシステムが開発されました。このオルガノイドシステムは、腫瘍表現型を調節する多様な腫瘍細胞内および外因性変化の役割を調査するためのユニークなプラットフォームを提供する。

Tags

癌研究、問題157、3D共同培養、肺癌、癌関連線維芽細胞、アチナー形態形成、腫瘍オルガノイド
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