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Journal / Biochemistry / Het ontcijferen van de structurele effecten van…
JoVE Journal
Biochemistry

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Het ontcijferen van de structurele effecten van het activeren van EGFR-somatische mutaties met moleculaire dynamicasimulatie

Article DOI: 10.3791/61125-v • 15:05 min • May 20th, 2020
May 20th, 2020 •
1, 2, 2,3,4, 1
1Structural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 2Medicity Research Laboratories and Institute of Biomedicine, University of Turku, 3Turku Bioscience Centre, University of Turku and Åbo Akademi University, 4Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital

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Het doel van dit protocol is om moleculaire dynamica simulaties te gebruiken om de dynamische structurele veranderingen die optreden als gevolg van activerende mutaties van het EGFR kinase eiwit te onderzoeken.

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Deze maand in JoVE Moleculaire dynamica simulaties Eiwit structuur analyses Epidermale groeifactor receptor familie Somatische mutaties Kanker
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