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Journal / Biochemistry / Het genereren van zelfassemblerende organoïden…
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Biochemistry

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JoVE Journal Biochemistry
Het genereren van zelfassemblerende organoïden voor het menselijk hart afgeleid van pluripotente stamcellen
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Journal (Biochemistry)
Spectrophotometric Methods for the Study of Eukaryotic Glycogen Metabolism
Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs
Journal (Biochemistry)
Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs
 
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Het genereren van zelfassemblerende organoïden voor het menselijk hart afgeleid van pluripotente stamcellen

Article DOI: 10.3791/63097-v • 08:56 min • September 15th, 2021
September 15th, 2021 •
1,2, 1,2, 1,2, 1,2, 1,2
1Institute for Quantitative Health Science and Engineering, Division of Developmental and Stem Cell Biology, Michigan State University, 2Department of Biomedical Engineering, College of Engineering, Michigan State University

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Hier beschrijven we een protocol om ontwikkelingsrelevante menselijke hartorganoïden (hHO's) efficiënt te maken met behulp van menselijke pluripotente stamcellen door zelforganisatie. Het protocol is gebaseerd op de sequentiële activering van ontwikkelingssignalen en produceert zeer complexe, functioneel relevante menselijke hartweefsels.

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Biochemie Nummer 175
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