Guest Editors
Eric Caragata
Johns Hopkins School of Public Health
<p>Dr. Eric Caragata. Dr. Caragata is interested in understanding the role of microorganisms in mosquito biology, and their impact on vector-borne diseases. He is particularly interested in understanding how <em>Wolbachia</em>-host metabolic interactions impact on host mosquito metabolism, immunity, and physiology. Dr. Caragata obtained his PhD at the University of Queensland, Australia in 2013. He then studied as a Postdoctoral Researcher at Instituto René Rachou, Belo Horizonte, Brazil from 2013 before joining the Dimopoulos group at Johns Hopkins University Malaria Research Institute in 2017.</p> <p> </p>
Yuemei Dong
Johns Hopkins School of Public Health
<p>Dr. Dong has over 16 years’ experience with molecular entomology of multiple mosquito species, and more than 25 years experience in molecular characterization of host-microbe interactions. Her current research interests focus on dissecting the molecular mechanisms of both anti-<em>Plasmodium </em>and anti-viral defenses of the mosquito immune system, and the interaction between pathogens, mosquito immune systems, and mosquito microbiota. Using biochemical, cellular biology, molecular biology, functional genomics, and more advanced insect transgenesis and genome editing techniques she has functionally dissected the interaction between <em>Plasmodium</em> parasites and Dengue/ Zika viruses with <em>Anopheles</em> and <em>Aedes</em> mosquitoes, respectively. These experiences have cemented Dr. Dong’s desire to apply the findings from basic research to potential application in controlling and combating vector-borne infectious diseases. Dr. Dong received her BS in biology from Peking University (known as Beida) which is a major research university and a member of the elite C9 League of Chinese universities. She earned her PhD in 1999 from the Institute of Botany, Chinese Academy of Sciences (CAS), where she worked on the plant-microbe interactions. Her academic education then continued at the University of Wisconsin-Madison, where she joined Dr. Triplett’s lab as a postdoctoral fellow working on molecular characterization of plant-microbe interactions and plant innate immune system. Driven by her strong interest in the vector-borne infectious diseases, in 2003 she joined the Malaria Research Institute at Johns Hopkins School of Public Health (JHSPH) working with Dr. Dimopoulos initially as a postdoctoral fellow, and now she is a faculty research associate at JHSPH. </p>
Collection Overview
Mosquitoes are the world’s deadliest animals. They spread a wide range of parasitic and viral diseases, including malaria and dengue, thereby causing millions of human deaths every year.. Insecticide resistance among mosquito populations from endemic regions is increasingly common. This exacerbates the need for new mosquito and pathogen control strategies,as well as novel diagnostic and surveillance techniques. Such advances will come through disseminating knowledge of mosquito biology; from routine colony maintenance to the intricacies of interactions between mosquitoes, pathogens and their human hosts. In this collection, we aim to demonstrate mosquito biological techniques for the purpose of helping researchers direct their research, and hopefully, discover new pathways to mosquito control.
The proposed topics for the collection will be grouped into two categories. (1) Understanding Mosquito Biology, including topics such as: rearing gnotobiotic mosquitoes, mapping the mosquito virome, mapping the mosquito brain, mosquito infection through artificial membrane feeding, understanding mosquito olfactory behavior, human malaria parasites culture, mosquito artificial diets, and mosquito hemocyte perfusion and functional studies. (2) Novel Mosquito Control Tools, including topics such as: mosquito larvicides and adulticides through natural products discovery, yeast-based mosquito larvicides that use RNA-interference, exploiting the microbiome to control mosquitoes, natural products discovery for potential malaria drugs and antiviral drugs, paratransgenesis through engineered symbiotic bacteria to block malaria transmission, next generation vector-borne disease surveillance tools, and tools for mosquito transgenesis and CRISPR/Cas9 genome editing.
Editorial
Novel Methodological Perspectives In The Study Of Mosquito Biology
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Cited by 1
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2022
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1W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, 2Department of Entomology & Nematology, Florida Medical Entomology Laboratory, Institute of Food and Agricultural Sciences, University of Florida
Articles
A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes
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2020
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1Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, College of Life Science, Hunan Normal University, 2State Key Laboratory of Developmental Biology of Freshwater Fish, Hunan Provincial Key Laboratory for Microbial Molecular Biology, College of Life Science, Hunan Normal University, 3Department of Infectious Diseases, the Second Xiangya Hospital, Central South University
Propagation of the Microsporidian Parasite Edhazardia aedis in Aedes aegypti Mosquitoes
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Cited by 6
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2020
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Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus
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Cited by 17
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2020
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Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding
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Cited by 68
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2020
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Feeding and Quantifying Animal-Derived Blood and Artificial Meals in Aedes aegypti Mosquitoes
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Cited by 17
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2020
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Preparing and Injecting Embryos of Culex Mosquitoes to Generate Null Mutations using CRISPR/Cas9
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Cited by 5
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2020
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Microinjection Method for Anopheles gambiae Embryos
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Cited by 11
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2021
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A Step-by-Step Guide to Mosquito Electroantennography
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Cited by 6
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2021
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Abstracts
Standardized Establishment, Quality-Controlled Maintenance, and Performance Monitoring of Anopheles arabiensis Colonies for Vector Biology
POUMACHU Yacouba*1
1OCEAC
Weather-Based Thresholds for Aedes albopictus Density in Suburban Shanghai: A Distributed Lag Nonlinear Modelling Approach
Yi Zhang1,
Haijian Wang1,
Chunwei Sun1,
Yingyu Yang1,
Miaomiao He1,
Zhixin Wu1,
Jianguo Tan*2,
Fan He*1
1Baoshan District Center for Disease Control and Prevention (Baoshan District Health Inspection Institute),
2Key Laboratory of Cities’ Mitigation and Adaptation to Climate Change in Shanghai; Key Laboratory of Urban Meteorology; China Meteorological Administration.