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Geautomatiseerde Sholl Analyse van Gedigitaliseerde Neuronale morfologie op meerdere schalen
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Capítulos
- 00:00Título
- 00:20Introduction
- 01:20Preparations for Automated Sholl Analysis
- 02:14Tracing Neurons in NeuronJ
- 04:52Using Bonfire to Build Preliminary .swc Files from NeuronJ Data
- 06:27Using NeuronStudio to Finalize .swc Files
- 07:57Using ‘bonfire’ to Extract Morphological Data and ‘bonfire_results’ to View the Data
- 09:06Using ‘bonfire_export’ to Export Data into Excel
- 11:21Conclusion
We hebben een computerprogramma ontwikkeld om neuronale morfologie te analyseren. In combinatie met de twee bestaande open source analyse-instrumenten, ons programma voert Sholl analyse en bepaalt het aantal neurieten, branche punten en neurieten tips. De analyses zijn zo uitgevoerd dat de lokale veranderingen in de morfologie van neurieten kan worden waargenomen.
Tags
Automated Sholl AnalysisDigitized Neuronal MorphologyMultiple ScalesNeuronsFunctionCommunicationInputsAction PotentialsNeuritesInformation ProcessingDendrite MorphologiesSignalingSpecialized FunctionsNeuronal NetworkAlterations In MorphologyFragmentationBranching PatternsDisease StatesAlzheimer’s DiseaseSchizophreniaMental RetardationFactors Shaping Dendrite MorphologiesNervous System Function And DysfunctionSholl AnalysisCounting Neurites And Branch TipsAxonsTime-consuming AnalysisVariabilityExperimenter BiasInconsistencyBonfire Program
