Graft Patency Rate
Graft Patency Rate - Related Videos
07:22
Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency
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Cited by 3 •
2017
This video demonstrates a model to study the development of myointimal hyperplasia after venous interposition surgery in rats.
07:37
Mouse Models for Graft Arteriosclerosis
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Cited by 17 •
2013
We describe protocols for our mouse graft arteriosclerois (GA) models which involve interposition of a mouse vessel segment into a recipient of the same inbred strain. By backcrossing additional genetic changes into the vessel donor, the model can assess the effect of specific genes on GA.
12:39
Implantation of Inferior Vena Cava Interposition Graft in Mouse Model
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Cited by 24 •
2014
To improve our knowledge of cellular and molecular neotissue formation, a murine model of the TEVG was recently developed. The grafts were implanted as infrarenal vena cava interposition grafts in C57BL/6 mice. This model achieves similar results to those achieved in our clinical investigation, but over a far shortened time-course.
11:17
Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
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Cited by 9 •
2015
A step-by-step protocol for the inter-positional placement of Tissue Engineered Vessels (TEVs) into the carotid artery of a sheep using end-to-end anastomosis and real-time digital assessment in vivo until animal sacrifice.
13:04
Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
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Cited by 13 •
2015
Here, we present a protocol to generate tissue engineered vessel grafts that are functional for grafting into mice by double seeding partially induced pluripotent stem cell (PiPSC) - derived smooth muscle cells and PiPSC - derived endothelial cells on a decellularized vessel scaffold bioreactor.
FAQs
Several processes can reduce graft patency over time, including narrowing, clot formation, intimal hyperplasia, and other vessel changes. These mechanisms may restrict blood flow enough to produce partial or complete occlusion. Consequently, a lower rate can reflect different forms of impaired flow rather than a single failure mechanism, which is important when interpreting treatment results.
Partial occlusion limits flow through the graft, whereas complete occlusion prevents continued passage through the treated pathway. Both conditions can reduce functional performance, but they represent different degrees of obstruction. Distinguishing these outcomes helps clinicians interpret follow-up findings and understand whether a graft has experienced progressive narrowing or a more extensive loss of flow.
A graft patency rate has meaning only in relation to the period over which it is assessed. Rates measured at different follow-up durations may describe different stages of graft durability and should not be treated as directly equivalent without considering timing. Defining the interval therefore supports clearer comparisons between procedures, grafts, and clinical outcomes.
Clinicians evaluate graft performance using imaging together with clinical follow-up. Imaging helps assess whether the graft pathway remains open, while clinical follow-up places that finding in the context of the patient's ongoing treatment course. Using both sources provides a broader basis for evaluating vascular or reconstructive procedures than relying on a single observation.
The measure is particularly relevant to vascular bypasses, dialysis access grafts, and other graft-based procedures in vascular and reconstructive medicine. In these settings, maintaining an open graft is closely related to continued function of the treated pathway. Tracking the rate helps clinicians assess whether a procedure is providing durable performance during follow-up.
Comparing patency rates allows clinicians to evaluate differences in graft performance and surgical outcomes. These comparisons can help inform graft selection and reveal opportunities to improve long-term durability. When paired with follow-up findings, the results also help identify whether narrowing, clot formation, intimal hyperplasia, or other vessel changes may be limiting success.