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Implantation of Inferior Vena Cava Interposition Graft in Mouse Model
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JoVE Journal Medicine
Implantation of Inferior Vena Cava Interposition Graft in Mouse Model

Implantation of Inferior Vena Cava Interposition Graft in Mouse Model

DOI:
10.3791/51632-v

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12:39 min

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June 04, 2014

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, , , , , ,
1Tissue Engineering Program and Surgical Research,Nationwide Children’s Hospital, 2Department of Cardiothoracic Surgery,Nationwide Children’s Hospital, 3Pediatric Surgery,Nationwide Children’s Hospital

Chapters

  • 00:05Title
  • 02:16Graft Manufacturing
  • 04:11Bone Marrow Mononuclear Cell Harvesting and Isolation
  • 05:56Implanting the Graft
  • 09:33Graft Characterization
  • 11:09Conclusion

Summary

Automatic Translation

Automatic Translation

To improve our knowledge of cellular and molecular neotissue formation, a murine model of the TEVG was recently developed. The grafts were implanted as infrarenal vena cava interposition grafts in C57BL/6 mice. This model achieves similar results to those achieved in our clinical investigation, but over a far shortened time-course.

Tags

Keywords: Inferior Vena CavaInterposition GraftMouse ModelBiodegradable ScaffoldBone Marrow Mononuclear CellsPatencyStenosis

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