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Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling
 

Quantitative Proteomics Using Reductive Dimethylation for Stable Isotope Labeling

Article DOI: 10.3791/51416
July 1st, 2014

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Summary July 1st, 2014

Stable isotope labeling of peptides by reductive dimethylation (ReDi labeling) is a rapid, inexpensive strategy for accurate mass spectrometry-based quantitative proteomics. Here we demonstrate a robust method for preparation and analysis of protein mixtures using the ReDi approach that can be applied to nearly any sample type.

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