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JoVE Journal
Bioengineering

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Production, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal Model
 

Production, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal Model

Article DOI: 10.3791/52693
May 18th, 2015

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Summary May 18th, 2015

This manuscript describes the production, characterization and potential uses of a tissue engineered 3D esophageal construct prepared from normal primary human esophageal fibroblast and squamous epithelial cells seeded within a de-cellularized porcine scaffold. The results demonstrate the formation of a mature stratified epithelium similar to the normal human esophagus.

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