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Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
 

Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis

Article DOI: 10.3791/52800
May 17th, 2015

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Summary May 17th, 2015

We describe a protocol for aortic interposition grafting in mice. The goal of the protocol is to provide a model with which to study pathological processes and therapeutic strategies relevant to alloimmune reactions in arteries and the resultant arterial changes that contribute to organ transplant failure.

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