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16:15 min
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October 11, 2014
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Here, we present a protocol to study the immunology of rejection. The surgical model presented reports a short operating time and a concise technique. Depending on the donor-recipient strain combination, the transplanted kidney may develop acute cellular rejection or chronic allograft damage, defined by interstitial fibrosis and tubular atrophy.
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Cite this Article
Tse, G. H., Hesketh, E. E., Clay, M., Borthwick, G., Hughes, J., Marson, L. P. Mouse Kidney Transplantation: Models of Allograft Rejection. J. Vis. Exp. (92), e52163, doi:10.3791/52163 (2014).
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