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Mouse Kidney Transplantation: Models of Allograft Rejection
Mouse Kidney Transplantation: Models of Allograft Rejection
JoVE Journal
Medicine
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JoVE Journal Medicine
Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

20,591 Views

16:15 min

October 11, 2014

DOI:

16:15 min
October 11, 2014

20548 Views
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Summary

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Here, we present a protocol to study the immunology of rejection. The surgical model presented reports a short operating time and a concise technique. Depending on the donor-recipient strain combination, the transplanted kidney may develop acute cellular rejection or chronic allograft damage, defined by interstitial fibrosis and tubular atrophy.

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