Journal
/
Medicine
/
Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection

Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection

DOI:
10.3791/57589-v

•

06:46 min

•

July 16, 2018

•

, , , , ,
1Center for Vascular and Inflammatory Diseases,University of Maryland School of Medicine, 2Department of Diagnostic Radiology and Nuclear Medicine,University of Maryland School of Medicine, 3Division of Vascular Surgery,University of Maryland School of Medicine

Chapters

  • 00:04Title
  • 00:34Surgical Procedure
  • 04:02Micro-CT Scanning and Image Analysis
  • 05:10Results: β-aminopropionitrile (BAPN) Treatment and Resulting Aneurysms
  • 06:13Conclusion

Summary

Automatic Translation

Automatic Translation

This article describes a detailed methodology of using a radiopaque lead-based silicone rubber to perfuse the murine vasculature for aortic diameter quantification in a mouse model of aortic aneurysm and dissection.

Tags

Keywords: Micro-CT AnalysisAortopathyMouse Modelβ-aminopropionitrileAortic AneurysmAortic DissectionVascular BiologyVessel SizeIn VivoEx VivoQuantificationSurgical ProcedureAnesthesiaIsofluraneIntracardiac PerfusionHemostatic ClampHeparinized PBSContrast Agent

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/57589?article_type=v

A New Murine Model of Endovascular Aortic Aneurysm Repair
check_url/57589?article_type=v

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
check_url/57589?article_type=v

The Helsinki Rat Microsurgical Sidewall Aneurysm Model
check_url/57589?article_type=v

Using the Sleeve Technique in a Mouse Model of Aortic Transplantation – An Instructional Video
check_url/57589?article_type=v

Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling
check_url/57589?article_type=v

Creation of a Rodent Model of Abdominal Aortic Aneurysm by Blocking Adventitial Vasa Vasorum Perfusion
check_url/57589?article_type=v

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
check_url/57589?article_type=v

Isometric Contractility Measurement of the Mouse Mesenteric Artery Using Wire Myography
check_url/57589?article_type=v

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
check_url/57589?article_type=v

Porcine Model of Infrarenal Abdominal Aortic Aneurysm

Read Article