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January 27, 2023
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Osteoclasts are key bone-resorbing cells in the body. This protocol describes a reliable method for the in vitro differentiation of osteoclasts from human peripheral blood monocytes. This method can be used as an important tool to further understand osteoclast biology in homeostasis and in diseases.
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Cite this Article
Riedlova, P., Sood, S., Goodyear, C. S., Ansalone, C. Differentiation of Functional Osteoclasts from Human Peripheral Blood CD14+ Monocytes. J. Vis. Exp. (191), e64698, doi:10.3791/64698 (2023).
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