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Designing a Bio-responsive Robot from DNA Origami
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Designing a Bio-responsive Robot from DNA Origami
DOI:

13:32 min

July 08, 2013

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Chapters

  • 00:05Title
  • 01:04Outline the Desired Shape and Scaffold Strand Path
  • 04:06Define Opening Mechanism Axes and Payload Attachment Sites
  • 05:45Add and Edit Staples
  • 07:55Create Loading Sites and Gates
  • 09:33Designing Gate Strands and Choosing Scaffold Sequence
  • 11:16Results: DNA Origami Nanorobot Design
  • 13:12Conclusion

Summary

Automatic Translation

DNA origami is a powerful method for fabricating precise nanoscale objects by programming the self-assembly of DNA molecules. Here, we describe how DNA origami can be utilized to design a robotic robot capable of sensing biological cues and responding by shape shifting, subsequently relayed to a desired effect.

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