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A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
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A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse

Article DOI: 10.3791/54658-v • 04:55 min • November 17th, 2016
November 17th, 2016 •
1, 1, 1, 1
1Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago

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The following article provides an easy, reproducible technique to effectively create a sustainable mouse model of limbal stem cell deficiency (LSCD). This animal model is useful in testing and comparing the efficacy of treatments for limbal stem cell diseases.

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Mouse Model Limbal Stem Cell Deficiency Mechanical Procedure Sustainable Model Chemical Injury Models Cellular And Molecular Level Novel Treatments Anesthesia Corneal Injury Tetracaine Hydrochloride Povidone Iodine Rotating Burr Bent Tweezers Stabilize The Eye Proctozing The Eye
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