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Journal / Neuroscience / Spinal Cord Transection in the Larval Zebrafish
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Neuroscience

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JoVE Journal Neuroscience
Spinal Cord Transection in the Larval Zebrafish
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Spinal Cord Transection in the Larval Zebrafish

Article DOI: 10.3791/51479-v • 06:57 min • May 21st, 2014
May 21st, 2014 •
1, 1
1Department of Neurobiology & Anatomy, University of Utah

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Summary
Automatic Translation

After spinal transection, adult zebrafish have functional recovery by six weeks post-injury. To take advantage of larval transparency and faster recovery, we present a method for transecting the larval spinal cord. After transection, we observe sensory recovery beginning at 2 days post-injury, and C-bend movement by 3 days post-injury.

Tags

Spinal Cord Transection Larval Zebrafish Axonal Regrowth Spinal Neurogenesis Sensory Recovery Motor Recovery Regeneration Genetic Tools Transparent Larval Zebrafish Reproducible Method Verifiable Transection C-bend Movement Free Swimming
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