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Journal / Genetics / Sekvens-specifikke og selektiv anerkendelse af…
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Genetics

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JoVE Journal Genetics
Sekvens-specifikke og selektiv anerkendelse af dobbelt-strenget RNA'er over enkeltstrenget RNA'er af kemisk modificerede peptid nukleinsyrer
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Sekvens-specifikke og selektiv anerkendelse af dobbelt-strenget RNA'er over enkeltstrenget RNA'er af kemisk modificerede peptid nukleinsyrer

Article DOI: 10.3791/56221-v • 09:04 min • September 21st, 2017
September 21st, 2017 •
*1, *1, 1
1Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University
* These authors contributed equally

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Vi rapporterer protokoller til syntese og rensning af peptid nukleinsyre (PNA) oligomerer indarbejde ændrede restkoncentrationer. De biokemiske og biofysiske metoder til karakterisering af anerkendelse af RNA dobbelthuse af de modificerede PNAs er beskrevet.

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