Waiting
登录处理中...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / 持续药物输注系统对小鼠脑内下丘脑胰岛素信号的研究…
JoVE Journal
Medicine

这篇 内容 是开放权限的.

JoVE Journal Medicine
持续药物输注系统对小鼠脑内下丘脑胰岛素信号的研究
Vacuum-Sealed Hot Water Bath Immersion for the Preparation of Anatomical and Surgical Cadaveric Bone Models
Journal (Medicine)
Vacuum-Sealed Hot Water Bath Immersion for the Preparation of Anatomical and Surgical Cadaveric Bone Models
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Journal (Medicine)
Learning Modern Laryngeal Surgery in a Dissection Laboratory
 
Click here for the English version

持续药物输注系统对小鼠脑内下丘脑胰岛素信号的研究

Article DOI: 10.3791/56410-v • 08:32 min • January 4th, 2018
January 4th, 2018 •
1,2, 1,2,3
1The Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University and National Health Research, 2Graduate Institute of Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, 3TMU research center for Neurotrauma and Neuroregeneration, College of Medical Science and Technology, Taipei Medical University

章节

总结概括
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

该协议研究的作用趋化因子 (c-c 主题) 配体 5 (CCL5) 在下丘脑通过提供拮抗剂,满足CCL5, 进入鼠标的大脑使用微渗透泵脑输液系统。这种瞬态抑制 CCL5 活动阻断了下丘脑胰岛素信号, 导致葡萄糖不耐受和外周系统胰岛素敏感性。

Tags

药物 问题 131 脑药物传递 微渗透泵 胰岛素耐受 葡萄糖代谢 趋化因子 (c-c 主题) 配体 5 (CCL5) 2 型糖尿病 (T2DM)
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter