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Journal / Chemistry / Fast-fase syntese af [4.4] Spirocyclic Oximes
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Fast-fase syntese af [4.4] Spirocyclic Oximes

Article DOI: 10.3791/58508-v • 05:15 min • February 6th, 2019
February 6th, 2019 •
1, 1, 1
1Department of Biology and Chemistry, Azusa Pacific University

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Her præsenterer vi en protokol for at påvise en effektiv metode til syntese af spirocyclic heterocycles. Den fem-trins proces udnytter fast-fase syntese og regenererende Michael linker strategier. Generelt vanskeligt at syntetisere, vi præsenterer en tilpasselig metode til syntese af spirocyclic molekyler ellers utilgængelige for andre moderne tilgange.

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Kemi spørgsmålet 144 fast-fase syntese regenererende Michael linker intramolekylære 1,3-dipolære cycloaddition spirocyclic heterocycles tricykliske mellemliggende høj diastereoselectivity
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