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Journal / Neuroscience / Transplantation av Chemogenetiskt konstruerade…
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Neuroscience

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JoVE Journal Neuroscience
Transplantation av Chemogenetiskt konstruerade kortikala Interneuron progenitorer till tidiga postnatal mus hjärnor
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Transplantation av Chemogenetiskt konstruerade kortikala Interneuron progenitorer till tidiga postnatal mus hjärnor

Article DOI: 10.3791/59568-v • 06:09 min • August 26th, 2019
August 26th, 2019 •
1,2, 3, 3, 1
1Nervous System Development and Homeostasis Laboratory, The Francis Crick Institute, 2Neuroscience Centre, Biomedical Sciences Research Centre "Al. Fleming", 3Centre for Developmental Neurobiology, King's College London

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Här presenterar vi ett protokoll, som syftar till att använda kemogenetiska verktyg för att manipulera aktiviteten av kortikala euron stamceller transplanteras in i cortex av tidiga postnatal möss.

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Neurovetenskap kortikala Interneuron ganglieblockerande Eminence Brain slice Electroporation intrakraniell injektioner designer receptorer uteslutande aktiveras av designer drugs (dreadd)
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