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JoVE Journal Cancer Research
Een syngeneïsch orthotopisch osteosarcoom Sprague Dawley Rat-model met amputatie om de metastasesnelheid te beheersen
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Een syngeneïsch orthotopisch osteosarcoom Sprague Dawley Rat-model met amputatie om de metastasesnelheid te beheersen

Article DOI: 10.3791/62139-v • 07:31 min • May 3rd, 2021
May 3rd, 2021 •
1,2,3,4, 5, 1, 6, 7, 8, 9, 10, 4, 1,2
1Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 3Department of Surgery, Johns Hopkins University School of Medicine, 4Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 5Program for Comparative Medicine, Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, 6Tuskegee College of Veterinary Medicine, 7Department of Human Pathology, Juntendo University Faculty of Medicine, 8Department of Surgery, Juntendo University Shizuoka Hospital, Juntendo University School of Medicine, 9Department of Urology, The Johns Hopkins School of Medicine, 10Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University Faculty of Medicine

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Hier wordt een syngenetische orthotopische implantatie gevolgd door een amputatieprocedure van het osteosarcoom met spontane pulmonale metastase beschreven die kan worden gebruikt voor preklinisch onderzoek van metastasebiologie en ontwikkeling van nieuwe therapieën.

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Kankeronderzoek nummer 171 sarcoom osteosarcoom orthotopische implantatie syngenetisch ratmodel longmetastase beenamputatie röntgenbeeldvorming
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