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Journal / Developmental Biology / 从特纳综合征（45XO）胎儿细胞生成诱导多能干细胞，用于与该综合征相关的神经功能障碍的下游建模…
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JoVE Journal Developmental Biology
从特纳综合征（45XO）胎儿细胞生成诱导多能干细胞，用于与该综合征相关的神经功能障碍的下游建模
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从特纳综合征（45XO）胎儿细胞生成诱导多能干细胞，用于与该综合征相关的神经功能障碍的下游建模

Article DOI: 10.3791/62240-v • 09:39 min • December 4th, 2021
December 4th, 2021 •
*1, *1, 2, 1, 1
1Manipal Institute of Regenerative Medicine, Manipal Academy of Higher Education, Manipal, Karnataka, India-576104, 2Department of Medical Genetics, Manipal Hospitals
* These authors contributed equally

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该协议描述了通过核切除递递递外体质粒，然后描述用于iPSC表征和神经元分化的方法，从胎儿组织成纤维细胞中产生整合的游离iPSCs。

Tags

发育生物学，第178期，重编程，人类诱导多能干细胞，非整倍体，先天性畸形，自发性胎儿死亡，特纳综合征，神经功能缺陷
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