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JoVE Journal Medicine
O-ring aortabånd versus traditionel tværgående aortaforsnævring til modellering af trykoverbelastningsinduceret hjertehypertrofi
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O-ring aortabånd versus traditionel tværgående aortaforsnævring til modellering af trykoverbelastningsinduceret hjertehypertrofi

Article DOI: 10.3791/64455-v • 09:24 min • October 6th, 2022
October 6th, 2022 •
1, 1, 2, 1, 1, 1, 2, 2, 1
1Department of Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Kiel, Partner Site Hamburg/Kiel/Lübeck, 2Internal Medicine III, German Centre for Cardiovascular Research, University Hospital Heidelberg, Partner Site Heidelberg/Mannheim

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Den nuværende protokol beskriver en ny teknik med aortabånd hos mus for at inducere trykoverbelastning hjertehypertrofi. Til banding anvendes en gummiring med en fast indvendig diameter. Denne nye teknik lover mindre varians og mere reproducerbare data til fremtidige eksperimenter.

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