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Journal / Bioengineering / Design of a Biaxial Mechanical Loading Bioreactor …
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Bioengineering

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Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Article DOI: 10.3791/50387-v • 08:04 min • April 25th, 2013
April 25th, 2013 •
1,2, 3, 1, 1,2
1Department of Orthopaedics, The Warren Alpert Brown Medical School of Brown University and the Rhode Island Hospital, 2Center for Restorative and Regenerative Medicine, VA Medical Center, Providence, RI, 3University of Texas Southwestern Medical Center

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Summary
Automatic Translation

We designed a novel mechanical loading bioreactor that can apply uniaxial or biaxial mechanical strain to a cartilage biocomposite prior to transplantation into an articular cartilage defect.

Tags

Biaxial Mechanical Loading Bioreactor Tissue Engineering Loading Device Uniaxial Mechanical Strain Biaxial Mechanical Strain Biocomposites Transplantation Bioreactor Native Mechanical Strains Load Cell Force Feedback Mechanical Testing Engineered Cartilage Constructs Loading Dose Amplitude Frequency Tissue Culture Incubator Tissue Culture Plate Precision-guided Laser Applications Orthogonal Stages Stepper Motor Actuators Closed-loop Stepper Motor Driver Micro-stepping Capabilities Polysulfone Loading Platen Moving Platform
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