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Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
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Kapitel
- 00:05Titel
- 00:47Preparation of Catheters and Uropathogenic E. coli for Infection
- 02:08Transurethral Instillation of Female Mice
- 03:43Transurethral Instillation of Male Mice
- 04:56Determination of CFU in Infected Organs
- 06:09Flow Cytometric Analysis of Bladder Tissue
- 08:31Results: Transurethral Catheterization to Induce Urinary Tract Infections
- 09:57Conclusion
The established model of transurethral catheterization of mice allows the study of bladder pathologies, including urinary tract infection, but can only be performed in females. A new model of male transurethral instillation, presented here, will enable research in an area marked by strong clinical and epidemiological differences between the sexes.
