JoVE Journal
Bioengineering
Bioengineering
Dieser Inhalt ist Open Access.
Kapitel
Summary
Here, we present a protocol for the preparation of two different forms of culture substrates utilizing type I collagen. Depending on how collagen is handled, collagen molecules either maintain two-dimensional, non-fibrous form or reassemble into three-dimensional, fibril form. Cell proliferation on type I collagen is drastically affected by fibril formation.