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Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Article DOI: 10.3791/62687-v • 07:12 min • August 2nd, 2021
August 2nd, 2021 •
1, 1, 1, 1, 1, 1
1Affiliated Brain Hospital of Guangzhou Medical University

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The present protocol describes the application of repetitive transcranial magnetic stimulation (rTMS), where a subregion of the dorsolateral prefrontal cortex (DLPFC) with the strongest functional anticorrelation with the subgenual anterior cingulate cortex (sgACC) was located as the stimulation target under the assistance of a fMRI-based neuronavigation system.

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RTMS Treatment Depression FMRI-based Targeting Method DLPFC Efficacy Heterogeneity Individualized Targeting Accuracy Of Positioning Treatment Response Subgenual Anterior Cingulate Cortex (sgACC) Region Of Interest (ROI) Gray Matter Probability Threshold Functional Connectivity (FC) Map Pearson's Correlation Coefficients Dorsolateral Prefrontal Cortex (DLPFC) Fisher's R-to-z Transformation Negative Functional Connectivity (FC) Peak Coordinate
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