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Biochemistry

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JoVE Journal Biochemistry
Massespektrometri og Luminogenic baserte tilnærminger for å karakter Fase I Metabolsk kompetansen
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Massespektrometri og Luminogenic baserte tilnærminger for å karakter Fase I Metabolsk kompetansen

Article DOI: 10.3791/55502-v • 10:44 min • March 28th, 2017
March 28th, 2017 •
1, 1
1Research and Development, British American Tobacco

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Metabolsk kompetansen av in vitro-systemer er en viktig forutsetning for biotransformasjonen og disponering av narkotika og giftstoffer. I denne protokollen beskriver vi anvendelse av referanse metabolske prober for å vurdere fase I metabolisme i cellekulturer.

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Biochemistry utgave 121 Bioaktive metabolisme, Toksikologi CYP
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